The best alternatives to Pyrun are Sticker Mule, Equals, and Today Scripts. If these 3 options don't work for you, we've listed a few more alternatives below.
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Today Scripts is a widget for running scripts in macOS's notification center. Make your Today View useful. Bash, python, ruby, even apple scripts. This open source app is made by SamRothCA 4 years ago. Now I made it works on the latest macOS.
A Python package to copy all your Kindle highlights and notes to a database in Notion. Plug in your Kindle device to your PC to run this script. Requires Python 3.9+ installed on your system.
You can use anything you can drag & drop on macOS as input for DropPy: Files & folders, emails, calendar items, images, URLs, images on websites, rich & plain text,.. DropPy pulls out all contained data and passes it through a series of reusable Python scripts (Tasks). Order and parameters are defined using a simple JSON format (Workflows).