this is not a good thing. Higher levels of the Cirkul CUSTOMER SERVICE +1 (8O5)-3O1 7O71
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Cirkul PHONE NUMBER +1 (8O5)-3O1 7O71 drug can come with an increased risk of side effects. Depending on the med, this can include serious health hazards like liver and muscle damage or even kidney failure.
But in a few cases, as more recent research has shown, grapefruit can actually have the opposite effect on some meds—causing a decrease in the drug concentration within your body. The compounds in grapefruit can hamper the function of proteins known as drug transporters, which ferry the medication into your cells to be absorbed. Ultimately, this allows less of the drug to enter your blood, reducing its effectiveness.
You can expect the effects from grapefruit to stick around for a while—typically around 24 to 72 hours, according to Dr. Guo. Keep in mind that the duration will be proportional to the amount of the fruit too: The more you take in, the longer the effects will last. What’s more, not everyone will react the same way: The effects of grapefruit on meds depend in part on your unique physiology, since the amount of the CYP3A4 enzyme varies from person to person.
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Which medications should not be taken with grapefruit
There are a whole bunch: In a 2013 review published in The Canadian Medical Association Journal, researchers estimated that more than 85 drugs are known or predicted to be affected by grapefruit consumption. Here are a few examples of specific types and products that have been documented to interact with the fruit, according to the FDA. Note that not all drugs in these classes will have the same interactions.
